ICD-10-CM · E00–E89Billable

ICD-10-CM Code E78.6

Lipoprotein deficiency

Source: CMS ICD-10-CM FY2026Effective Reviewed by the D3rx Clinical Billing Team

Diagnosis information

Billable

Yes

Valid for claim submission

Chapter

E00–E89

Endocrine, nutritional and metabolic diseases

Risk adjustment

None

Not risk-adjustable (V28)

Coding or sequencing E78.6? Ask D3 free.Ask

Procedures commonly billed with E78.6

CPT/HCPCS procedures frequently paired with E78.6 on claims. The diagnosis helps support medical necessity for the service, but documentation, the service performed, and payer/CMS policy all apply — link each line item to the diagnosis that best documents why it was needed.

  • 80000Laboratory Test 80000
  • 80050Laboratory Test 80050
  • 80100Laboratory Test 80100
  • 80150Laboratory Test 80150
  • 80200Laboratory Test 80200
  • 80250Laboratory Test 80250
  • 80300Laboratory Test 80300
  • 80350Laboratory Test 80350

More codes in the E78 category

Other billable ICD-10-CM codes in the same category as E78.6. Coding to the highest specificity the documentation supports is what keeps a claim clean — pick the child code that most precisely matches the diagnosis.

  • E78.00Pure hypercholesterolemia, unspecified
  • E78.010Homozygous familial hypercholesterolemia [HoFH]
  • E78.011Heterozygous familial hypercholesterolemia [HeFH]
  • E78.019Familial hypercholesterolemia, unspecified
  • E78.1Pure hyperglyceridemia
  • E78.2Mixed hyperlipidemia
  • E78.3Hyperchylomicronemia
  • E78.41Elevated Lipoprotein(a)
  • E78.49Other hyperlipidemia
  • E78.5Hyperlipidemia, unspecified
  • E78.70Disorder of bile acid and cholesterol metabolism, unspecified
  • E78.71Barth syndrome

Documentation & coding notes

  • E78.6 is a billable/specific ICD-10-CM code — it can be reported as a primary or secondary diagnosis when the documentation supports it. Code to the highest level of specificity the record allows.
  • Always verify the code against the current ICD-10-CM Official Guidelines and the payer's coverage policy before submitting — coverage, medical necessity edits, and sequencing rules vary by payer.

Related E00–E89 codes

Questions about coding E78.6?

Ask D3 — free AI backed by CMS, ICD-10-CM, and major-payer data. Get a cited answer in seconds, no signup.

Medical coding disclaimer

ICD-10-CM codes and descriptions shown are from the CMS FY2026 official code set and HCC mappings from the CMS-HCC V28 model (payment year 2026), shown for educational reference. Official Guidelines, payer coverage, medical-necessity edits, and sequencing rules vary. Always verify with the current ICD-10-CM Official Guidelines and the payer before submitting claims. D3rx is not responsible for coding or billing outcomes.