ICD-10-CM · J00–J99BillableHCC279

ICD-10-CM Code J45.51

Severe persistent asthma with (acute) exacerbation

Source: CMS ICD-10-CM FY2026Effective Reviewed by the D3rx Clinical Billing Team

Diagnosis information

Billable

Yes

Valid for claim submission

Chapter

J00–J99

Diseases of the respiratory system

Risk adjustment

HCC

HCC279

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HCC risk adjustment (CMS-HCC V28)

HCC279Severe Persistent Asthma
Model CMS-HCC V28Payment year 2026

In CMS's Hierarchical Condition Category (HCC) model — the risk-adjustment model for Medicare Advantage (Part C) — a documented and submitted J45.51 may contribute to a member's risk score (subject to the CMS-HCC hierarchy and edits), which helps drive the plan's capitated payment for that patient. To count, the diagnosis must be supported to the MEAT standard (Monitored, Evaluated, Assessed, Treated) and reported on an eligible face-to-face encounter at least once each calendar year — risk scores reset annually.

More codes in the J45 category

Other billable ICD-10-CM codes in the same category as J45.51. Coding to the highest specificity the documentation supports is what keeps a claim clean — pick the child code that most precisely matches the diagnosis.

  • J45.20Mild intermittent asthma, uncomplicated
  • J45.21Mild intermittent asthma with (acute) exacerbation
  • J45.22Mild intermittent asthma with status asthmaticus
  • J45.30Mild persistent asthma, uncomplicated
  • J45.31Mild persistent asthma with (acute) exacerbation
  • J45.32Mild persistent asthma with status asthmaticus
  • J45.40Moderate persistent asthma, uncomplicated
  • J45.41Moderate persistent asthma with (acute) exacerbation
  • J45.42Moderate persistent asthma with status asthmaticus
  • J45.50Severe persistent asthma, uncomplicated
  • J45.52Severe persistent asthma with status asthmaticus
  • J45.901Unspecified asthma with (acute) exacerbation

Documentation & coding notes

  • J45.51 is a billable/specific ICD-10-CM code — it can be reported as a primary or secondary diagnosis when the documentation supports it. Code to the highest level of specificity the record allows.
  • J45.51 is risk-adjustable: it maps to HCC279 in the CMS-HCC V28 model (payment year 2026), the risk-adjustment model for Medicare Advantage (Part C). For the diagnosis to contribute to a member's risk score it must survive the CMS-HCC hierarchy and edits, be documented to the MEAT standard (Monitored, Evaluated, Assessed, Treated), and be submitted on an eligible face-to-face encounter at least once per calendar year.
  • Always verify the code against the current ICD-10-CM Official Guidelines and the payer's coverage policy before submitting — coverage, medical necessity edits, and sequencing rules vary by payer.

Related J00–J99 codes

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Medical coding disclaimer

ICD-10-CM codes and descriptions shown are from the CMS FY2026 official code set and HCC mappings from the CMS-HCC V28 model (payment year 2026), shown for educational reference. Official Guidelines, payer coverage, medical-necessity edits, and sequencing rules vary. Always verify with the current ICD-10-CM Official Guidelines and the payer before submitting claims. D3rx is not responsible for coding or billing outcomes.